Aescin, Escin; HPLC 98%

CAS No.: 6805-41-0

Molecular Formula: C₅₅H₈₆O₂₄ Molecular Weight: 1131.26 EINECS No.: 229-880-6

Applications of Escin (Aescin)

1. Pharmaceutical and Clinical Applications

(1) Chronic Venous Insufficiency & Varicose Veins

• Enhances venous tone and improves venous blood return, relieving symptoms such as leg heaviness, pain, swelling and fatigue.
• Reduces capillary permeability and decreases fluid exudation to alleviate lower extremity edema.
• Used for the treatment of varicose veins, phlebitis, deep vein thrombosis (adjunctive) and post-thrombotic syndrome.

(2) Anti-edema for Trauma and Postoperative Recovery

• Exerts significant anti-inflammatory, anti-exudative and detumescent effects.
• Indicated for swelling caused by fractures, sprains, contusions and various surgical operations.
• Accelerates hematoma absorption, relieves pain and shortens the recovery period.

(3) Cerebral Edema and Intracranial Hypertension

• Reduces blood-brain barrier permeability to alleviate cerebral edema and lower intracranial pressure.
• Used as adjunctive therapy for traumatic brain injury, cerebral infarction, cerebral hemorrhage and concussion.

(4) Hemorrhoids

• Improves perianal venous return and relieves hemorrhoidal swelling, pain, bleeding and inflammation.
• Applied in oral and topical preparations for internal, external and mixed hemorrhoids.

(5) Anti-inflammatory and Analgesic Effects

• Provides anti-inflammatory and analgesic activity for arthritis, soft tissue inflammation and gouty arthritis.
• Alleviates nerve root edema in lumbar disc herniation and relieves radiating pain and numbness.

2. Cosmetics and Personal Care

• Used in body contouring and slimming products to reduce edema and improve skin firmness.
• Applied in eye care products to relieve dark circles, eye bags and puffiness.
• Possesses soothing and anti-redness properties for sensitive and post-sun skin care.

3. Main Pharmacological Properties

• Venotonic: strengthens venous wall elasticity and contractility
• Anti-exudative: stabilizes vascular endothelium
• Anti-inflammatory: inhibits inflammatory mediators
• Anti-edematous: promotes lymphatic drainage
• Antioxidant: scavenges free radicals and protects cells

4. Product Features

• Natural plant extract from horse chestnut seeds.
• High safety profile and good tolerance.
• Widely used in oral, injectable and topical pharmaceutical formulations.
• Also applied in functional cosmetics for venous circulation and anti-edema benefits.