α-Lipoic Acid

α-Lipoic Acid

CAS No. 1077-28-7

Molecular Formula: C₈H₁₄O₂S₂

Molecular Weight: 206.33

EINECS No.: 214-071-2

Applications of Alpha-Lipoic Acid (ALA)

CAS No. 1077-28-7 | Formula: C₈H₁₄O₂S₂ | MW: 206.33 | EINECS: 214-071-2

Diabetic complications

Approved for the treatment of diabetic peripheral neuropathy to relieve numbness, pain, burning, and paresthesia; improves nerve conduction and blood flow. Also helps improve insulin sensitivity and supports glycemic control in type 2 diabetes.
Neuroprotection

Crosses the blood–brain barrier, scavenges free radicals, and supports neuronal function. Studied for adjunctive use in stroke, Parkinson’s disease, Alzheimer’s disease, and alcohol-related nerve damage.
Cardiovascular & metabolic support

Protects vascular endothelium, helps improve lipid profiles, reduces oxidative stress in myocardial ischemia, and supports liver health in fatty liver disease.
Adjuvant in oncology

Used to reduce oxidative damage during chemotherapy and radiotherapy, while protecting normal cells.

Anti-aging & anti-wrinkle

Neutralizes UV-induced free radicals, promotes collagen synthesis, and reduces fine lines and skin sagging.
Brightening & anti-pigmentation

Inhibits tyrosinase activity, helping to lighten dark spots and even skin tone.
Anti-inflammatory & barrier repair

Reduces redness, soothes sensitive skin, and improves post-inflammatory hyperpigmentation.
Used in serums, creams, masks, and oral beauty supplements.

Antioxidant support

Recycles vitamins C and E and glutathione, earning it the nickname “the antioxidant of antioxidants.”
Energy & fatigue relief

Acts as a mitochondrial coenzyme to enhance cellular energy metabolism.
Weight management

Improves insulin sensitivity and helps regulate appetite.
Common forms: capsules, tablets, and powder (typical daily dose: 100–600 mg).

Food additive: Antioxidant and color preservative for oils, fats, and meat products.
Feed additive: Improves antioxidant capacity and growth performance in livestock.