Boc-L-Pyroglutamic acid ethyl ester

Boc-L-Pyroglutamic acid ethyl ester/ Boc-Pyr-Oet

CAS No.: 144978-12-1

An important chiral amino acid derivative, mainly used as a pharmaceutical intermediate for peptide drugs, and widely applied in organic synthesis and new drug R&D.

1. Intermediate for Peptide Synthesis

   As a key chiral building block in solid-phase peptide synthesis (SPPS), the Boc group stabilizes the amino group and is used to construct complex peptides and cyclic peptide drugs.

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3. Synthesis of Anti-HIV, Antitumor and Neurological Drugs

   With its stable chiral pyrrolidone structure, it is commonly used as a key precursor for anti-HIV, antitumor and central nervous system drugs.

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5. Intermediate for New Drugs such as β-Lactamase Inhibitors

   It can be used in the synthesis of intermediates related to novel antibacterial enhancers such as Avibactam.

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7. Chiral Ligands and Asymmetric Catalysis

   Used as a chiral catalyst or ligand precursor to control stereoselectivity and prepare compounds with high optical purity.
9. Development of Cosmetic Ingredients

   Its derivatives can be used as moisturizing and anti-aging active ingredients in the R&D of high-end skincare products.