Methoxycarbonyl-L-tert-leucine

CAS No.: 162537-11-3
Molecular Formula: C₈H₁₅NO₄
Molecular Weight: 189.21
EINECS No.: 431-620-3

Applications:

1. Pharmaceutical

Key intermediate for Atazanavir (ATV), an HIV protease inhibitor

Used in synthesis of anti-HCV drugs (Boceprevir, Telaprevir)

Amino-protected chiral building block for peptide drugs (anticancer, antibacterial, anti-inflammatory)

Provides steric hindrance & stability, prolongs half-life in vivo

2. Chemical & R&D

Chiral intermediate for asymmetric synthesis & complex molecules

Biochemical research: enzyme inhibitors & SAR studies

Pesticide intermediate for environmentally friendly agrochemicals

3. Key Advantages

High optical purity, stable, good solubility, easy deprotection.