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Calcium Citrate

Calcium Citrate

Calcium Citrate

CAS No.: 813-94-5
Molecular Formula: C₁₂H₁₀Ca₃O₁₄
Molecular Weight: 498.43
EINECS No.: 212-391-7

Applications of Calcium Citrate:

1. Pharmaceutical & Clinical Applications 

(1) Calcium Supplement & Deficiency Treatment Used for prevention and treatment of calcium deficiency in children, adolescents, pregnant and lactating women, and the elderly.

Suitable for patients with hypochlorhydria, atrophic gastritis, and those taking acid-suppressing drugs (e.g., proton pump inhibitors).
(2) Skeletal Health Osteoporosis: combined with vitamin D to increase bone mineral density and reduce fracture risk in postmenopausal women and elderly patients.
Osteomalacia & Rickets: assists in bone mineralization and improves bone metabolism disorders.
Helps relieve symptoms such as muscle spasms, leg cramps and bone pain caused by calcium deficiency.
(3) Other Clinical Uses Adjuvant therapy for hyperphosphatemia in chronic kidney disease by binding dietary phosphate.

Used in the treatment of hypoparathyroidism to maintain normal blood calcium levels.


2. Food & Nutritional Supplements Widely used in dietary supplements: tablets, capsules, chewables, powders and liquid formulations.
Added to milk powder, dairy products, cereal foods, beverages and functional foods for calcium fortification.

Preferred calcium source in supplements for elderly and people with poor gastric acid secretion.


3. Food Additive Industry Used as a food stabilizer, coagulant and acidity regulator in processed foods.

Applied in dairy products, canned foods, jellies, desserts and baked goods to improve texture and stability.


4. Key Characteristics & Advantages Highly soluble in water and well absorbed independent of gastric acid.
Higher absorption rate and better gastrointestinal tolerance compared with calcium carbonate.
Lower risk of gastrointestinal discomfort (constipation, bloating).
Suitable for long-term daily supplementation.

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